I have acne prone skin as well, and I tried the accutane stuff. I had horrible side effects, so then my dermatologist put me on an anti-biotic but that ended up giving me severe and chronic yeast infections. So now I found this great stuff called blemish guard made by a company called Kal (you can get it at wholefoods or online). Its a supplement that is all-natural and organic. I love it! And for spot treatment I was using the pink lotion by Mario Badescu, which is really expensive. Then I found the company that actually makes the stuff- they are called Professional Solutions and they call it Blemex. It's about half the price if you buy it directly from them. That stuff is the best- I put it on the few pimples I get before I go to bed and the next day they are gone. Sometimes it might take two days. That combination is what's worked best for me, but then again everyone's body is different...