no, lol I'm not completely dipigmented yet, I don't want to be completely dipigmented. But I can certainly see how this can eventually make someone depigmented. But the good thing is it lightens shade by shade, I'll stop once I get to an ideal shade. I think I'll get there honestly in a few months. I like Drake's skin tone. but with both mono and mequinol once you get to a certain color, doesn't mean you'll stay there. People who have completely depigmented with both had some pigment come back. But I think that can be avoided with a little maintance. I'm pretty sure this is what I read.