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Discussion Starter #1
I am very pleased to let everyone know that if you are willing to look bad to look good there is a real tangible and much less expensive alternative to laser resurfacing. This is particularly true to body skin damage from the sun since this cannot typically be treated by the most effective laser resurfacing and chemical (deep) peel methods.

This is as of yet off-label use but a study was released in the Lancet (A British Medical Journal) which has unequivocally shown that Efudix (flourouracil) is an effective topical to reverse wrinkles, discolouration and damage to the skin. It is approved as of now for the treatment of pre-cancerous lesions known as acitinic-keratoses. Flourouracil is also used as 5-FU for internal chemotherapy and also is now being touted as an alternative in its injection form to treat hypertrophic and keloid as well as subcutaneous scarring. It inhibits abnormal proliferation of cells thereby returning them to their original form.

The treatment with flourouracil cream is not without serious side-effects. It ONLY is good to treat extrinsic skin aging as it will not work on simply aged skin but on sun damage, which almost all of us have, it will reverse most of this. The side effects are serious in that it causes a very uneven and unpredictable red, flaky and irritated skin. It eventually (after about 4 weeks) calms and after that it will calm down. The effects are permanent once achieved so unlike tretinoin (retin-a) it is not a lifetime commitment but rather a treatment.
 

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Wow!! I have never been on Alldaychemist site until right now. I had no idea you could get such things without a Rx. Doesn't look like a smart thing to do considering all the side effects most Rx could have!! why risk it?

Using Latisse compared to taking or using a topical without a Rx is not the same to me. I guess using RA is minor too, as long as you know what you are doing. But to use all the other things that are on that site?? Crazy in my book-
 

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I'm not naming names, but on one particular online pharmacy site you can get all your transgender meds without Rx! That's a leeeeettle scary to me!!



Skin | care | talk
 

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Wow!! I have never been on Alldaychemist site until right now. I had no idea you could get such things without a Rx. Doesn't look like a smart thing to do considering all the side effects most Rx could have!! why risk it?

Using Latisse compared to taking or using a topical without a Rx is not the same to me. I guess using RA is minor too, as long as you know what you are doing. But to use all the other things that are on that site?? Crazy in my book-
Wow you've never been to allday before?? I just assumed you had with all the talk about folks getting their tretinoin there.
 

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Wow you've never been to allday before?? I just assumed you had with all the talk about folks getting their tretinoin there.
Nope, I have a Rx for all my goodies. I just clicked on the link you provided, and OMG!!! Had no idea!!

gosh give me some more to look at-
and they wonder why this world has problems??!!!
 

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I'm sorry - but selling that chemotherapeutic drug for folks to smear on their skin without a Rx is ridiculous. Yet another drug that should not be used by pregnant or nursing mothers being sold indiscriminately at the click of a button - no questions asked!
 

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Discussion Starter #12
OK--yes I am going to try it! I am going to try it though in a limited way on some of my sun damaged areas (freckled). I will be doing it as I have called my dermatologist who is a friend and she was actually really interested in the article, read it and agreed it is a future possibility. It will actually just peel your skin as a deep chemical peel does but over time. This is not a new or controversial or even risky therapy as severe reactions in themselves will get people to stop. This is used routinley to treat acitinic-keratoses, though the product Solareze which is diclofenac sodium is now used more often due to less irritation. The irritiation is much more substantial than with tretinoin so by this alone I think many people will NOT opt to do this.

As for ADC selling this--well I think it is relatively harmless in comparison to viagra which can cause serious health problems, tramadol, fiorocet and many other drugs, INCLUDING TYLENOL-sold as paracetamol in UK and also under acetaminophen in USA. Tylenol is more deadly than most and few people realise this. I think that one thing people need to understand is that in India, like Asia, some of these things are easily obtained without prescription by walking into a drug store or chemists. Agree or not it is a cultural difference and as many Europeans know places like Spain also had a long standing different "pharmacy culture" than the rest of Europe in that it was not dissimilar to Asia. We tend to think just because something is prescription it is harmful and needs to be dispensed by someone but if it is OTC it is ok. The facts do not support this and many things that are prescription will become OTC and vice-versa (allergy meds--some have gone OTC and others are very close to becoming prescription only!).

So while I understand the concern I also think that the issue is that we do live in a global world so as long as incoming parcels are not 100% monitored things like retin-a or flourouracil are relatively low priority when people are shipping dilaudid and morphine, steroids and HORMONES as Fawnie has pointed out into other countries. The internal meds worry me more than anything external and personally I would NEVER ingest anything from a foreign online-pharmacy!
 

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Yep-

hows the weather in Hotlanta today?
 

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Maybe Lexi is knowledgeable and has done her research and can make informed decisions. Fine - and I am buying Retin-A without a Rx. We have both done our research, as have many others on this site.

My problem is with the fact that that site and others sell Rx drugs indiscriminately to anyone who presents an acceptable form of payment. How many gals who want beautiful skin know that the agents that work best can also harm their unborn child or one that they may be nursing? These are the folks at risk and they do not even know it.

And the fact that ADC is posting a phony questionnaire as window dressing says that they know that there is a problem.
 

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Discussion Starter #17
Maybe Lexi is knowledgeable and has done her research and can make informed decisions. Fine - and I am buying Retin-A without a Rx. We have both done our research, as have many others on this site.

My problem is with the fact that that site and others sell Rx drugs indiscriminately to anyone who presents an acceptable form of payment. How many gals who want beautiful skin know that the agents that work best can also harm their unborn child or one that they may be nursing? These are the folks at risk and they do not even know it.

And the fact that ADC is posting a phony questionnaire as window dressing says that they know that there is a problem.
I agree but until the laws catch up to the technology we are where we are so to speak. There will always be drug dealers as well. I am a strong proponent of legalisation of all substances but then again I am libertarian. I just feel like free access gives people less reason to source things from shady places and also would be able to open conversation with a pharmacist for example which is better than nobody. That said--with this Mirecka I DOUBT most people can screw up. I say that because severe red, peeling and irritated skin is almosta guarantee. NOTHING as mild as the worst of retin-a reactions, much, much worse in fact. A person with little or no knowledge as to what will happen would likely be freaked out by just how severe the reaction is with 5-FU so abuse potential is low, in fact treatment likelihood even under a physicians care is most likely to be discontinued.
 

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The bottom line for companies that sell this is money. They're outside the US, therefore our laws do not apply to them until they hit our borders, and most go unnoticed. I think anyone who uses a drug, whether it's for internal or topical use, or is taken with an Rx or over-the-counter, must be aware and careful with their own health. We can no longer depend solely on doctors to tell us what is right for us. Of course we must take their educated opinions into account, but plenty of medications that were FDA approved have caused problems down the line. Getting something with an Rx does not guarantee it's safety. While it might guarantee the product is what it claims to be, there are a host of other risks. As long as there is profit to be made, there will be a market for this kind of thing.
 

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Discussion Starter #20
You are a brave soul Lexi. I will be curious to see how you do with this. Will you do before and after pic's?
If I knew how I would. I am debating whether to wait though as I am afraid of it being so warm now and having to go out as I want to try it on my decolletage which will be very exposed. It is a very harsh substance and should not be taken lightly. It causes irritation, redness and pain!!! WEEKS after the 4-8 week treatment. What it does is damages the skin then encourages repair-so it is like ablative laser but what I like about the prospect of this is that unlike ablative laser which has far superior results to all other lasers, it can be used all over the body. The downside is that those with intrinsic aging do not seem to benefit, only sun damage.
 
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